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Pharmaceutical Raw Materials Aicar CAS 2627-69-2 Cardiovascular Diseases Treatment Acadesine

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Pharmaceutical Raw Materials Aicar CAS 2627-69-2 Cardiovascular Diseases Treatment Acadesine

Place of Origin : Wuhan, Hubei, China
Brand Name : YCGC
Certification : ISO, KOSHER
MOQ : Negotiable
Price : Negotiable
Packaging Details : As you require
Delivery Time : 12 hours within your payment is received
Payment Terms : T/T, Western Union, Money Gram, Bitcoin
Supply Ability : 1000kg/month
Model Number : 2627-69-2
storage temp. : 20°C
CAS : 2627-69-2
MF : C9H14N4O5
MW : 258.23
EINECS : 220-097-5
mp : 214-215 °C
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Pharmaceutical Raw Materials Aicar CAS 2627-69-2 Cardiovascular Diseases Treatment Acadesine

Quick Detail

mp214-215 °C
storage temp.20°C
solubility H2O>10 mg/mL

AICAR Usage And Synthesis
adenosine regulating agents Acadesine is the prototype of a new class of compounds termed adenosine regulating agents. Acadesine is a purine nucleosid analogue that enters the myocyte and is immediately phosphorylated to ZMP (AICA ribotide), which is further metabolised to Inosine mono-phosphate (an intermediate in the synthesis ofadenosine triphosphate (ATP) and guanosine triphos-phate).

Claims that acadesine may serve as a substrate for ATP synthesis and result in repletion of myocardial ATP were supported by some studies and refuted by others. Because acadesine may be a precursor in the synthesis of myocardial ATP it was proposed as a possible agent of myocardial protection during ischaemia, particularly because myocardial ATP depletion has been linked to cell death.

Chemical Properties Solid
Usage glucose uptake stimulant; AMPK activator
Usage AICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) hav e been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
Biological Activity Cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes.
AICAR Preparation Products And Raw materials

Product Categories: Bases & Related Reagents;Carbohydrates & Derivatives;Nucleotides;Protein Kinase;ARASINE;Cardiovascular APIs;PI3K/Akt/mTOR

3. Our Advantage:

Quality products at fair price
1)Standard: Enterprise Standard
2)All Purity≥ 99%
3)We are manufacturer and can provide high quality products with factory price.

Fast and safe delivery
1)Parcel can be sent out in 24 hours after payment. Tracking number available
2)Secure and discreet shipment. Various transportation methods for your choice.
3)Customs pass rate ≥ 99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

We have customers around the world
1)Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2)Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

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